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Overexpression of denticleless E3 ubiquitin protein ligase homolog (DTL) is related to poor outcome in gastric carcinoma

BACKGROUND: Denticleless E3 ubiquitin protein ligase homolog (DTL) has been identified in amplified region (1q32) of several cancers and has an oncogenic function. In this study, we tested whether DTL acts as a cancer-promoting gene through its activation/overexpression in gastric cancer (GC). METHO...

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Detalles Bibliográficos
Autores principales: Kobayashi, Hiroki, Komatsu, Shuhei, Ichikawa, Daisuke, Kawaguchi, Tsutomu, Hirajima, Shoji, Miyamae, Mahito, Okajima, Wataru, Ohashi, Takuma, Kosuga, Toshiyuki, Konishi, Hirotaka, Shiozaki, Atsushi, Fujiwara, Hitoshi, Okamoto, Kazuma, Tsuda, Hitoshi, Otsuji, Eigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742199/
https://www.ncbi.nlm.nih.gov/pubmed/26472028