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A TCRβ Repertoire Signature Can Predict Experimental Cerebral Malaria

Cerebral Malaria (CM) is associated with a pathogenic T cell response. Mice infected by P. berghei ANKA clone 1.49 (PbA) developing CM (CM(+)) present an altered PBL TCR repertoire, partly due to recurrently expanded T cell clones, as compared to non-infected and CM(-) infected mice. To analyse the...

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Detalles Bibliográficos
Autores principales: Mariotti-Ferrandiz, Encarnita, Pham, Hang-Phuong, Dulauroy, Sophie, Gorgette, Olivier, Klatzmann, David, Cazenave, Pierre-André, Pied, Sylviane, Six, Adrien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742225/
https://www.ncbi.nlm.nih.gov/pubmed/26844551
http://dx.doi.org/10.1371/journal.pone.0147871