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Screening of Drug Metabolizing Enzymes for the Ginsenoside Compound K In Vitro: An Efficient Anti-Cancer Substance Originating from Panax Ginseng

Ginsenoside compound K (CK), a rare ginsenoside originating from Panax Ginseng, has been found to possess unique pharmacological activities specifically as anti-cancers. However, the role of cytochrome P450s (CYPs) in the metabolism of CK is unclear. In this study, we screened the CYPs for the metab...

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Detalles Bibliográficos
Autores principales: Xiao, Jian, Chen, Dan, Lin, Xiu-Xian, Peng, Shi-Fang, Xiao, Mei-Fang, Huang, Wei-Hua, Wang, Yi-Cheng, Peng, Jing-Bo, Zhang, Wei, Ouyang, Dong-Sheng, Chen, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742234/
https://www.ncbi.nlm.nih.gov/pubmed/26845774
http://dx.doi.org/10.1371/journal.pone.0147183