CHROMOTHRIPSIS FROM DNA DAMAGE IN MICRONUCLEI

Genome sequencing has uncovered a new mutational phenomenon in cancer and congenital disorders called chromothripsis. Chromothripsis is characterized by extensive genomic rearrangements and an oscillating pattern of DNA copy number levels, all curiously restricted to one or a few chromosomes. The me...

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Detalles Bibliográficos
Autores principales: Zhang, Cheng-Zhong, Spektor, Alexander, Cornils, Hauke, Francis, Joshua M., Jackson, Emily K., Liu, Shiwei, Meyerson, Matthew, Pellman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742237/
https://www.ncbi.nlm.nih.gov/pubmed/26017310
http://dx.doi.org/10.1038/nature14493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742237/
https://www.ncbi.nlm.nih.gov/pubmed/26017310
http://dx.doi.org/10.1038/nature14493

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