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G-CSF is a key modulator of MDSC and could be a potential therapeutic target in colitis-associated colorectal cancers

Granulocyte colony-stimulating factor (G-CSF) is an essential regulator of neutrophil trafficking and is highly expressed in multiple tumors. Myeloid derived suppressor cells (MDSCs) promote neoplastic progression through multiple mechanisms by immune suppression. Despite the findings of G-CSF funct...

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Detalles Bibliográficos
Autores principales: Li, Wenbin, Zhang, Xinghua, Chen, Yongkang, Xie, Yibin, Liu, Jiancheng, Feng, Qiang, Wang, Yi, Yuan, Wei, Ma, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742385/
https://www.ncbi.nlm.nih.gov/pubmed/26797765
http://dx.doi.org/10.1007/s13238-015-0237-2