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G-CSF is a key modulator of MDSC and could be a potential therapeutic target in colitis-associated colorectal cancers
Granulocyte colony-stimulating factor (G-CSF) is an essential regulator of neutrophil trafficking and is highly expressed in multiple tumors. Myeloid derived suppressor cells (MDSCs) promote neoplastic progression through multiple mechanisms by immune suppression. Despite the findings of G-CSF funct...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742385/ https://www.ncbi.nlm.nih.gov/pubmed/26797765 http://dx.doi.org/10.1007/s13238-015-0237-2 |