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Neuroblastomas Vary Widely in Their Sensitivities to Herpes Simplex Virotherapy Unrelated to Virus Receptors and Susceptibility

Although most high-risk neuroblastomas are responsive to chemotherapy, relapse is common and long-term survival is less than 40%, underscoring the need for more effective treatments. We evaluated the responsiveness of 12 neuroblastoma cell lines to the Δγ(1)34.5 attenuated oncolytic HSV, Seprehvir (...

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Detalles Bibliográficos
Autores principales: Wang, Pin-Yi, Swain, Hayley M., Kunkler, Anne L., Chen, Chun-Yu, Hutzen, Brian J., Arnold, Michael A., Streby, Keri A., Collins, Margaret H., Dipasquale, Betsy, Stanek, Joseph R., Conner, Joe, van Kuppevelt, Toin H., Glorioso, Joseph C., Grandi, Paola, Cripe, Timothy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742391/
https://www.ncbi.nlm.nih.gov/pubmed/26583803
http://dx.doi.org/10.1038/gt.2015.105