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Liquid Jet Delivery Method Featuring S100A1 Gene Therapy in the Rodent Model Following Acute Myocardial Infarction

The S100A1 gene is a promising target enhancing contractility and survival post myocardial infarction (MI). Achieving sufficient gene delivery within safety limits is a major translational problem. This proof of concept study evaluates viral-mediated S100A1 overexpression featuring a novel liquid je...

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Detalles Bibliográficos
Autores principales: Fargnoli, Anthony S., Katz, Michael G., Williams, Richard D., Kendle, Andrew P., Steuerwald, Nury, Bridges, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742412/
https://www.ncbi.nlm.nih.gov/pubmed/26461176
http://dx.doi.org/10.1038/gt.2015.100