IGF-1 Receptor Differentially Regulates Spontaneous and Evoked Transmission via Mitochondria at Hippocampal Synapses

The insulin-like growth factor-1 receptor (IGF-1R) signaling is a key regulator of lifespan, growth, and development. While reduced IGF-1R signaling delays aging and Alzheimer’s disease progression, whether and how it regulates information processing at central synapses remains elusive. Here, we sho...

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Detalles Bibliográficos
Autores principales: Gazit, Neta, Vertkin, Irena, Shapira, Ilana, Helm, Martin, Slomowitz, Edden, Sheiba, Maayan, Mor, Yael, Rizzoli, Silvio, Slutsky, Inna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742535/
https://www.ncbi.nlm.nih.gov/pubmed/26804996
http://dx.doi.org/10.1016/j.neuron.2015.12.034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742535/
https://www.ncbi.nlm.nih.gov/pubmed/26804996
http://dx.doi.org/10.1016/j.neuron.2015.12.034

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