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Single-Cell RNA-Sequencing Reveals a Continuous Spectrum of Differentiation in Hematopoietic Cells

The transcriptional programs that govern hematopoiesis have been investigated primarily by population-level analysis of hematopoietic stem and progenitor cells, which cannot reveal the continuous nature of the differentiation process. Here we applied single-cell RNA-sequencing to a population of hem...

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Detalles Bibliográficos
Autores principales: Macaulay, Iain C., Svensson, Valentine, Labalette, Charlotte, Ferreira, Lauren, Hamey, Fiona, Voet, Thierry, Teichmann, Sarah A., Cvejic, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742565/
https://www.ncbi.nlm.nih.gov/pubmed/26804912
http://dx.doi.org/10.1016/j.celrep.2015.12.082