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Modulation of Melanogenesis by Heme Oxygenase-1 via p53 in Normal Human Melanocytes

As a key regulator of melanogenesis, p53 controls microphthalmia-associated transcription factor (MITF) and tyrosinase expression. The anti-oxidant enzyme heme oxygenase-1 (HO-1) is induced by various forms of cellular stress and diverse oxidative stimuli. However, few studies have examined the role...

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Detalles Bibliográficos
Autores principales: Lim, Hee-Sun, Jin, Suna, Yun, Sook Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chonnam National University Medical School 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742609/
https://www.ncbi.nlm.nih.gov/pubmed/26865999
http://dx.doi.org/10.4068/cmj.2016.52.1.45