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Modulation of Melanogenesis by Heme Oxygenase-1 via p53 in Normal Human Melanocytes
As a key regulator of melanogenesis, p53 controls microphthalmia-associated transcription factor (MITF) and tyrosinase expression. The anti-oxidant enzyme heme oxygenase-1 (HO-1) is induced by various forms of cellular stress and diverse oxidative stimuli. However, few studies have examined the role...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Chonnam National University Medical School
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742609/ https://www.ncbi.nlm.nih.gov/pubmed/26865999 http://dx.doi.org/10.4068/cmj.2016.52.1.45 |