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Significance of KIT exon 17 mutation depends on mutant level rather than positivity in core-binding factor acute myeloid leukemia

KIT exon 17 mutation is a poor prognostic factor in core-binding factor acute myeloid leukemia. However, the mutation detection method used for risk assessment is not assigned. It is necessary to verify the analytical and clinical performance before applying new methods. Herein, we firstly applied a...

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Detalles Bibliográficos
Autores principales: Jang, W, Yoon, J-H, Park, J, Lee, G D, Kim, J, Kwon, A, Choi, H, Han, K, Nahm, C H, Kim, H-J, Min, W-S, Kim, M, Kim, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742633/
https://www.ncbi.nlm.nih.gov/pubmed/26771813
http://dx.doi.org/10.1038/bcj.2015.116