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The Adenovirus E4-ORF3 Protein Stimulates SUMOylation of General Transcription Factor TFII-I to Direct Proteasomal Degradation

Modulation of host cell transcription, translation, and posttranslational modification processes is critical for the ability of many viruses to replicate efficiently within host cells. The human adenovirus (Ad) early region 4 open reading frame 3 (E4-ORF3) protein forms unique inclusions throughout...

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Detalles Bibliográficos
Autores principales: Bridges, Rebecca G., Sohn, Sook-Young, Wright, Jordan, Leppard, Keith N., Hearing, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742714/
https://www.ncbi.nlm.nih.gov/pubmed/26814176
http://dx.doi.org/10.1128/mBio.02184-15