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Hepatic adenylate cyclase 3 is upregulated by Liraglutide and subsequently plays a protective role in insulin resistance and obesity

OBJECTIVE: Recent studies have demonstrated that adenylate cyclase 3 (AC3) has a protective role in obesity. This gene resides at the pathway with glucagon-like peptide (GLP)-1. Liraglutide is a GLP-1 analog and has independent glucose and body weight (BW)-reducing effects. In the present study, we...

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Detalles Bibliográficos
Autores principales: Liang, Y, Li, Z, Liang, S, Li, Y, Yang, L, Lu, M, Gu, H F, Xia, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742720/
https://www.ncbi.nlm.nih.gov/pubmed/26807509
http://dx.doi.org/10.1038/nutd.2015.37