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Exploration of multiple Sortase A protein conformations in virtual screening

Methicillin resistant Staphylococcus aureus (MRSA) has become a major health concern which has brought about an urgent need for new therapeutic agents. As the S. aureus Sortase A (SrtA) enzyme contributes to the adherence of the bacteria to the host cells, inhibition thereof by small molecules could...

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Detalles Bibliográficos
Autores principales: Gao, Chunxia, Uzelac, Ivana, Gottfries, Johan, Eriksson, Leif A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742773/
https://www.ncbi.nlm.nih.gov/pubmed/26846342
http://dx.doi.org/10.1038/srep20413