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Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection

Tetherin/BST-2 is a host restriction factor that inhibits retrovirus release from infected cells in vitro by tethering nascent virions to the plasma membrane. However, contradictory data exists on whether Tetherin inhibits acute retrovirus infection in vivo. Previously, we reported that Tetherin-med...

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Detalles Bibliográficos
Autores principales: Li, Sam X., Barrett, Bradley S., Guo, Kejun, Kassiotis, George, Hasenkrug, Kim J., Dittmer, Ulf, Gibbert, Kathrin, Santiago, Mario L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742778/
https://www.ncbi.nlm.nih.gov/pubmed/26846717
http://dx.doi.org/10.1038/srep20425