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Targeting arginase-II protects mice from high-fat-diet-induced hepatic steatosis through suppression of macrophage inflammation

Nonalcoholic fatty liver disease (NAFLD) associates with obesity and type 2 diabetes. Hypoactive AMP-activated protein kinase (AMPK), hyperactive mammalian target of rapamycin (mTOR) signaling, and macrophage-mediated inflammation are mechanistically linked to NAFLD. Studies investigating roles of a...

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Detalles Bibliográficos
Autores principales:	Liu, Chang, Rajapakse, Angana G., Riedo, Erwin, Fellay, Benoit, Bernhard, Marie-Claire, Montani, Jean-Pierre, Yang, Zhihong, Ming, Xiu-Fen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742779/ https://www.ncbi.nlm.nih.gov/pubmed/26846206 http://dx.doi.org/10.1038/srep20405

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