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Balancing Immune Protection and Immune Pathology by CD8(+) T-Cell Responses to Influenza Infection

Influenza A virus (IAV) is a significant human pathogen causing annual epidemics and periodic pandemics. CD8(+) cytotoxic T lymphocyte (CTL)-mediated immunity contributes to the clearance of virus-infected cells, and CTL immunity targeting the conserved internal proteins of IAVs is a key protection...

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Detalles Bibliográficos
Autores principales: Duan, Susu, Thomas, Paul G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742794/
https://www.ncbi.nlm.nih.gov/pubmed/26904022
http://dx.doi.org/10.3389/fimmu.2016.00025