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Activated mast cells promote differentiation of B cells into effector cells

Based on the known accumulation of mast cells (MCs) in B cell-dependent inflammatory diseases, including rheumatoid arthritis, we hypothesized that MCs directly modulate B cells. We show here that degranulated, and to a lesser extent naïve or IgE-sensitized, MCs activate both naïve and B cell recept...

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Detalles Bibliográficos
Autores principales: Palm, Anna-Karin E., Garcia-Faroldi, Gianni, Lundberg, Marcus, Pejler, Gunnar, Kleinau, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742803/
https://www.ncbi.nlm.nih.gov/pubmed/26847186
http://dx.doi.org/10.1038/srep20531