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Activated mast cells promote differentiation of B cells into effector cells
Based on the known accumulation of mast cells (MCs) in B cell-dependent inflammatory diseases, including rheumatoid arthritis, we hypothesized that MCs directly modulate B cells. We show here that degranulated, and to a lesser extent naïve or IgE-sensitized, MCs activate both naïve and B cell recept...
Autores principales: | Palm, Anna-Karin E., Garcia-Faroldi, Gianni, Lundberg, Marcus, Pejler, Gunnar, Kleinau, Sandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742803/ https://www.ncbi.nlm.nih.gov/pubmed/26847186 http://dx.doi.org/10.1038/srep20531 |
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