miR-203 inhibits proliferation and self-renewal of leukemia stem cells by targeting survivin and Bmi-1

Drug resistance is one of the leading causes of failed cancer therapy in the treatment of acute myeloid leukemia. Although the mechanisms of resistance are poorly understood, they may be related to the presence of leukemia stem cells (LSCs). Down-regulation of the miR-203 reportedly contributes to o...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Zhou, Shu-yan, Yan, Hai-zhao, Xu, Dan-dan, Chen, Hai-xuan, Wang, Xiao-yan, Wang, Xiao, Liu, Yu-ting, Zhang, Li, Wang, Sheng, Zhou, Peng-jun, Fu, Wu-yu, Ruan, Bi-bo, Ma, Dong-lei, Wang, Ying, Liu, Qiu-ying, Ren, Zhe, Liu, Zhong, Zhang, Rong, Wang, Yi-fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742816/
https://www.ncbi.nlm.nih.gov/pubmed/26847520
http://dx.doi.org/10.1038/srep19995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742816/
https://www.ncbi.nlm.nih.gov/pubmed/26847520
http://dx.doi.org/10.1038/srep19995

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