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Structural basis for two-step glucose trimming by glucosidase II involved in ER glycoprotein quality control

The endoplasmic reticulum (ER) has a sophisticated protein quality control system for the efficient folding of newly synthesized proteins. In this system, a variety of N-linked oligosaccharides displayed on proteins serve as signals recognized by series of intracellular lectins. Glucosidase II catal...

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Detalles Bibliográficos
Autores principales: Satoh, Tadashi, Toshimori, Takayasu, Yan, Gengwei, Yamaguchi, Takumi, Kato, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742823/
https://www.ncbi.nlm.nih.gov/pubmed/26847925
http://dx.doi.org/10.1038/srep20575