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Cisplatin resistance in gastric cancer cells is associated with HER2 upregulation-induced epithelial-mesenchymal transition

Cisplatin remains to be primary chemotherapeutic drug for gastric cancer patients, especially for advanced stage ones. However, primary or acquired resistance often occurs with the mechanisms being not well understood, which results in relapse of the cancer and poor survival. Herein, we found that H...

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Detalles Bibliográficos
Autores principales: Huang, Dongsheng, Duan, Hongying, Huang, Hao, Tong, Xiangmin, Han, Yong, Ru, Guoqing, Qu, Like, Shou, Chengchao, Zhao, Zhongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742832/
https://www.ncbi.nlm.nih.gov/pubmed/26846307
http://dx.doi.org/10.1038/srep20502