A monoclonal antibody against KCNK9 K(+) channel extracellular domain inhibits tumour growth and metastasis

Two-pore domain potassium (K2P) channels act to maintain cell resting membrane potential—a prerequisite for many biological processes. KCNK9, a member of K2P family, is implicated in cancer, owing to its overexpression in human tumours and its ability to promote neoplastic cell survival and growth....

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Detalles Bibliográficos
Autores principales: Sun, Han, Luo, Liqun, Lal, Bachchu, Ma, Xinrong, Chen, Lieping, Hann, Christine L., Fulton, Amy M., Leahy, Daniel J., Laterra, John, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742836/
https://www.ncbi.nlm.nih.gov/pubmed/26842342
http://dx.doi.org/10.1038/ncomms10339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742836/
https://www.ncbi.nlm.nih.gov/pubmed/26842342
http://dx.doi.org/10.1038/ncomms10339

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