Cargando…
A monoclonal antibody against KCNK9 K(+) channel extracellular domain inhibits tumour growth and metastasis
Two-pore domain potassium (K2P) channels act to maintain cell resting membrane potential—a prerequisite for many biological processes. KCNK9, a member of K2P family, is implicated in cancer, owing to its overexpression in human tumours and its ability to promote neoplastic cell survival and growth....
Autores principales: | Sun, Han, Luo, Liqun, Lal, Bachchu, Ma, Xinrong, Chen, Lieping, Hann, Christine L., Fulton, Amy M., Leahy, Daniel J., Laterra, John, Li, Min |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742836/ https://www.ncbi.nlm.nih.gov/pubmed/26842342 http://dx.doi.org/10.1038/ncomms10339 |
Ejemplares similares
-
2-Aminoethoxydiphenyl borate activates the mechanically gated human KCNK channels KCNK 2 (TREK-1), KCNK 4 (TRAAK), and KCNK 10 (TREK-2)
por: Beltrán, Leopoldo, et al.
Publicado: (2013) -
Identification and characterization of two zebrafish Twik related potassium channels, Kcnk2a and Kcnk2b
por: Nasr, Nathalie, et al.
Publicado: (2018) -
Functional analysis of missense variants in the TRESK (KCNK18) K(+) channel
por: Andres-Enguix, Isabelle, et al.
Publicado: (2012) -
Effects of the ventilatory stimulant, doxapram on human TASK‐3 (KCNK9, K2P9.1) channels and TASK‐1 (KCNK3, K2P3.1) channels
por: Cunningham, Kevin P., et al.
Publicado: (2019) -
Opening and Closing of KcnkØ Potassium Leak Channels Is Tightly Regulated
por: Zilberberg, Noam, et al.
Publicado: (2000)