Genome-scale study reveals reduced metabolic adaptability in patients with non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease (NAFLD) is a major risk factor leading to chronic liver disease and type 2 diabetes. Here we chart liver metabolic activity and functionality in NAFLD by integrating global transcriptomic data, from human liver biopsies, and metabolic flux data, measured across the...

Descripción completa

Detalles Bibliográficos
Autores principales: Hyötyläinen, Tuulia, Jerby, Livnat, Petäjä, Elina M., Mattila, Ismo, Jäntti, Sirkku, Auvinen, Petri, Gastaldelli, Amalia, Yki-Järvinen, Hannele, Ruppin, Eytan, Orešič, Matej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742839/
https://www.ncbi.nlm.nih.gov/pubmed/26839171
http://dx.doi.org/10.1038/ncomms9994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742839/
https://www.ncbi.nlm.nih.gov/pubmed/26839171
http://dx.doi.org/10.1038/ncomms9994

Ejemplares similares