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Genome-scale study reveals reduced metabolic adaptability in patients with non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease (NAFLD) is a major risk factor leading to chronic liver disease and type 2 diabetes. Here we chart liver metabolic activity and functionality in NAFLD by integrating global transcriptomic data, from human liver biopsies, and metabolic flux data, measured across the...

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Detalles Bibliográficos
Autores principales:	Hyötyläinen, Tuulia, Jerby, Livnat, Petäjä, Elina M., Mattila, Ismo, Jäntti, Sirkku, Auvinen, Petri, Gastaldelli, Amalia, Yki-Järvinen, Hannele, Ruppin, Eytan, Orešič, Matej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742839/ https://www.ncbi.nlm.nih.gov/pubmed/26839171 http://dx.doi.org/10.1038/ncomms9994

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