Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4

MicroRNAs regulate the maladaptation of endothelial cells (ECs) to naturally occurring disturbed blood flow at arterial bifurcations resulting in arterial inflammation and atherosclerosis in response to hyperlipidemic stress. Here, we show that reduced endothelial expression of the RNAse Dicer, whic...

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Detalles Bibliográficos
Autores principales: Hartmann, Petra, Zhou, Zhe, Natarelli, Lucia, Wei, Yuanyuan, Nazari-Jahantigh, Maliheh, Zhu, Mengyu, Grommes, Jochen, Steffens, Sabine, Weber, Christian, Schober, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742841/
https://www.ncbi.nlm.nih.gov/pubmed/26837267
http://dx.doi.org/10.1038/ncomms10521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742841/
https://www.ncbi.nlm.nih.gov/pubmed/26837267
http://dx.doi.org/10.1038/ncomms10521

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