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Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis

Autophagy is a conserved, intracellular, lysosomal degradation pathway. While mechanistic aspects of this pathway are increasingly well defined, it remains unclear how autophagy modulation impacts normal physiology. It is, however, becoming clear that autophagy may play a key role in regulating deve...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoting, Fleming, Angeleen, Ricketts, Thomas, Pavel, Mariana, Virgin, Herbert, Menzies, Fiona M., Rubinsztein, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742842/
https://www.ncbi.nlm.nih.gov/pubmed/26837467
http://dx.doi.org/10.1038/ncomms10533