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Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis
Autophagy is a conserved, intracellular, lysosomal degradation pathway. While mechanistic aspects of this pathway are increasingly well defined, it remains unclear how autophagy modulation impacts normal physiology. It is, however, becoming clear that autophagy may play a key role in regulating deve...
Autores principales: | Wu, Xiaoting, Fleming, Angeleen, Ricketts, Thomas, Pavel, Mariana, Virgin, Herbert, Menzies, Fiona M., Rubinsztein, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742842/ https://www.ncbi.nlm.nih.gov/pubmed/26837467 http://dx.doi.org/10.1038/ncomms10533 |
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