Steric interactions lead to collective tilting motion in the ribosome during mRNA–tRNA translocation

Translocation of mRNA and tRNA through the ribosome is associated with large-scale rearrangements of the head domain in the 30S ribosomal subunit. To elucidate the relationship between 30S head dynamics and mRNA–tRNA displacement, we apply molecular dynamics simulations using an all-atom structure-b...

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Detalles Bibliográficos
Autores principales: Nguyen, Kien, Whitford, Paul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742886/
https://www.ncbi.nlm.nih.gov/pubmed/26838673
http://dx.doi.org/10.1038/ncomms10586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742886/
https://www.ncbi.nlm.nih.gov/pubmed/26838673
http://dx.doi.org/10.1038/ncomms10586

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