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Steric interactions lead to collective tilting motion in the ribosome during mRNA–tRNA translocation
Translocation of mRNA and tRNA through the ribosome is associated with large-scale rearrangements of the head domain in the 30S ribosomal subunit. To elucidate the relationship between 30S head dynamics and mRNA–tRNA displacement, we apply molecular dynamics simulations using an all-atom structure-b...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742886/ https://www.ncbi.nlm.nih.gov/pubmed/26838673 http://dx.doi.org/10.1038/ncomms10586 |