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Transplanted neurons integrate into adult retinas and respond to light

Retinal ganglion cells (RGCs) degenerate in diseases like glaucoma and are not replaced in adult mammals. Here we investigate whether transplanted RGCs can integrate into the mature retina. We have transplanted GFP-labelled RGCs into uninjured rat retinas in vivo by intravitreal injection. Transplan...

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Detalles Bibliográficos
Autores principales: Venugopalan, Praseeda, Wang, Yan, Nguyen, Tu, Huang, Abigail, Muller, Kenneth J., Goldberg, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742891/
https://www.ncbi.nlm.nih.gov/pubmed/26843334
http://dx.doi.org/10.1038/ncomms10472