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Inhibition of airway surface fluid absorption by cholinergic stimulation

In upper airways airway surface liquid (ASL) depth and clearance rates are both increased by fluid secretion. Secretion is opposed by fluid absorption, mainly via the epithelial sodium channel, ENaC. In static systems, increased fluid depth activates ENaC and decreased depth inhibits it, suggesting...

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Detalles Bibliográficos
Autores principales: Joo, Nam Soo, Krouse, Mauri E., Choi, Jae Young, Cho, Hyung-Ju, Wine, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742893/
https://www.ncbi.nlm.nih.gov/pubmed/26846701
http://dx.doi.org/10.1038/srep20735