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Inhibition of airway surface fluid absorption by cholinergic stimulation
In upper airways airway surface liquid (ASL) depth and clearance rates are both increased by fluid secretion. Secretion is opposed by fluid absorption, mainly via the epithelial sodium channel, ENaC. In static systems, increased fluid depth activates ENaC and decreased depth inhibits it, suggesting...
Autores principales: | Joo, Nam Soo, Krouse, Mauri E., Choi, Jae Young, Cho, Hyung-Ju, Wine, Jeffrey J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742893/ https://www.ncbi.nlm.nih.gov/pubmed/26846701 http://dx.doi.org/10.1038/srep20735 |
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