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Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression

The coordinated activity of DNA replication factors is a highly dynamic process that involves ubiquitin-dependent regulation. In this context, the ubiquitin-directed ATPase CDC-48/p97 recently emerged as a key regulator of chromatin-associated degradation in several of the DNA metabolic pathways tha...

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Detalles Bibliográficos
Autores principales: Franz, André, Pirson, Paul A., Pilger, Domenic, Halder, Swagata, Achuthankutty, Divya, Kashkar, Hamid, Ramadan, Kristijan, Hoppe, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743000/
https://www.ncbi.nlm.nih.gov/pubmed/26842564
http://dx.doi.org/10.1038/ncomms10612