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Cellular delivery and photochemical release of a caged inositol-pyrophosphate induces PH-domain translocation in cellulo

Inositol pyrophosphates, such as diphospho-myo-inositol pentakisphosphates (InsP(7)), are an important family of signalling molecules, implicated in many cellular processes and therapeutic indications including insulin secretion, glucose homeostasis and weight gain. To understand their cellular func...

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Detalles Bibliográficos
Autores principales: Pavlovic, Igor, Thakor, Divyeshsinh T., Vargas, Jessica R., McKinlay, Colin J., Hauke, Sebastian, Anstaett, Philipp, Camuña, Rafael C., Bigler, Laurent, Gasser, Gilles, Schultz, Carsten, Wender, Paul A., Jessen, Henning J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743007/
https://www.ncbi.nlm.nih.gov/pubmed/26842801
http://dx.doi.org/10.1038/ncomms10622