Structural basis for human PRDM9 action at recombination hot spots

The multidomain zinc finger (ZnF) protein PRDM9 (PRD1–BF1–RIZ1 homologous domain-containing 9) is thought to influence the locations of recombination hot spots during meiosis by sequence-specific DNA binding and trimethylation of histone H3 Lys4. The most common variant of human PRDM9, allele A (hPR...

Descripción completa

Detalles Bibliográficos
Autores principales: Patel, Anamika, Horton, John R., Wilson, Geoffrey G., Zhang, Xing, Cheng, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743056/
https://www.ncbi.nlm.nih.gov/pubmed/26833727
http://dx.doi.org/10.1101/gad.274928.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743056/
https://www.ncbi.nlm.nih.gov/pubmed/26833727
http://dx.doi.org/10.1101/gad.274928.115

Ejemplares similares