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Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress

Little is known about how cells ensure DNA replication in the face of RNA polymerase II (RNAPII)-mediated transcription, especially under conditions of replicative stress. Here we present genetic and proteomic analyses from budding yeast that uncover links between the DNA replication checkpoint sens...

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Detalles Bibliográficos
Autores principales: Poli, Jérôme, Gerhold, Christian-Benedikt, Tosi, Alessandro, Hustedt, Nicole, Seeber, Andrew, Sack, Ragna, Herzog, Franz, Pasero, Philippe, Shimada, Kenji, Hopfner, Karl-Peter, Gasser, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743062/
https://www.ncbi.nlm.nih.gov/pubmed/26798134
http://dx.doi.org/10.1101/gad.273813.115