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Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress
Little is known about how cells ensure DNA replication in the face of RNA polymerase II (RNAPII)-mediated transcription, especially under conditions of replicative stress. Here we present genetic and proteomic analyses from budding yeast that uncover links between the DNA replication checkpoint sens...
Autores principales: | Poli, Jérôme, Gerhold, Christian-Benedikt, Tosi, Alessandro, Hustedt, Nicole, Seeber, Andrew, Sack, Ragna, Herzog, Franz, Pasero, Philippe, Shimada, Kenji, Hopfner, Karl-Peter, Gasser, Susan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743062/ https://www.ncbi.nlm.nih.gov/pubmed/26798134 http://dx.doi.org/10.1101/gad.273813.115 |
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