Transforming growth factor-beta 1 produced by vascular smooth muscle cells predicts fibrosis in the gastrocnemius of patients with peripheral artery disease

BACKGROUND: Lower leg ischemia, myopathy, and limb dysfunction are distinguishing features of peripheral artery disease (PAD). The myopathy of PAD is characterized by myofiber degeneration in association with extracellular matrix expansion, and increased expression of transforming growth factor-beta...

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Detalles Bibliográficos
Autores principales: Ha, Duy M., Carpenter, Lauren C., Koutakis, Panagiotis, Swanson, Stanley A., Zhu, Zhen, Hanna, Mina, DeSpiegelaere, Holly K., Pipinos, Iraklis I., Casale, George P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743093/
https://www.ncbi.nlm.nih.gov/pubmed/26847457
http://dx.doi.org/10.1186/s12967-016-0790-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743093/
https://www.ncbi.nlm.nih.gov/pubmed/26847457
http://dx.doi.org/10.1186/s12967-016-0790-3

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