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Alternating bipolar field stimulation identifies muscle fibers with defective excitability but maintained local Ca(2+) signals and contraction

BACKGROUND: Most cultured enzymatically dissociated adult myofibers exhibit spatially uniform (UNI) contractile responses and Ca(2+) transients over the entire myofiber in response to electric field stimuli of either polarity applied via bipolar electrodes. However, some myofibers only exhibit contr...

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Detalles Bibliográficos
Autores principales: Hernández-Ochoa, Erick O., Vanegas, Camilo, Iyer, Shama R., Lovering, Richard M., Schneider, Martin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743112/
https://www.ncbi.nlm.nih.gov/pubmed/26855765
http://dx.doi.org/10.1186/s13395-016-0076-8