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sciReptor: analysis of single-cell level immunoglobulin repertoires

BACKGROUND: The sequencing of immunoglobulin (Ig) transcripts from single B cells yields essential information about Ig heavy:light chain pairing, which is lost in conventional bulk sequencing experiments. The previously limited throughput of single-cell approaches has recently been overcome by the...

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Detalles Bibliográficos
Autores principales: Imkeller, Katharina, Arndt, Peter F., Wardemann, Hedda, Busse, Christian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743164/
https://www.ncbi.nlm.nih.gov/pubmed/26847109
http://dx.doi.org/10.1186/s12859-016-0920-1