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From competency to dormancy: a 3D model to study cancer cells and drug responsiveness

BACKGROUND: The heterogeneous and dynamic tumor microenvironment has significant impact on cancer cell proliferation, invasion, drug response, and is probably associated with entering dormancy and recurrence. However, these complex settings are hard to recapitulate in vitro. METHODS: In this study,...

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Detalles Bibliográficos
Autores principales: Fang, Josephine Y., Tan, Shih-Jye, Wu, Yi-Chen, Yang, Zhi, Hoang, Ba X., Han, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743174/
https://www.ncbi.nlm.nih.gov/pubmed/26847768
http://dx.doi.org/10.1186/s12967-016-0798-8