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From competency to dormancy: a 3D model to study cancer cells and drug responsiveness
BACKGROUND: The heterogeneous and dynamic tumor microenvironment has significant impact on cancer cell proliferation, invasion, drug response, and is probably associated with entering dormancy and recurrence. However, these complex settings are hard to recapitulate in vitro. METHODS: In this study,...
Autores principales: | Fang, Josephine Y., Tan, Shih-Jye, Wu, Yi-Chen, Yang, Zhi, Hoang, Ba X., Han, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743174/ https://www.ncbi.nlm.nih.gov/pubmed/26847768 http://dx.doi.org/10.1186/s12967-016-0798-8 |
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