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Krüppel-like factor 4 expression in oral carcinoma cells and hypermethylation at the gene promoter
BACKGROUND: Krüppel-like factor 4 (KLF4) is a transcription factor regulating proliferation-differentiation balance of epithelium, and down-regulated in less-differentiated and advanced oral carcinomas. Although the expression is inactivated by the promoter hypermethylation in malignant tumor cells,...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743192/ https://www.ncbi.nlm.nih.gov/pubmed/26847634 http://dx.doi.org/10.1186/s12903-016-0172-5 |