Krüppel-like factor 4 expression in oral carcinoma cells and hypermethylation at the gene promoter

BACKGROUND: Krüppel-like factor 4 (KLF4) is a transcription factor regulating proliferation-differentiation balance of epithelium, and down-regulated in less-differentiated and advanced oral carcinomas. Although the expression is inactivated by the promoter hypermethylation in malignant tumor cells,...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Ayumi, Kuroyama, Karen, Tokura, Ayana, Saito, Atsushi, Arikawa, Huhga, Hasebe, Takahisa, Usui, Dai, Yamaguchi, Kosuke, Chiba, Tadashige, Imai, Kazushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743192/
https://www.ncbi.nlm.nih.gov/pubmed/26847634
http://dx.doi.org/10.1186/s12903-016-0172-5

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