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The role of structural parameters in DNA cyclization

BACKGROUND: The intrinsic bendability of DNA plays an important role with relevance for myriad of essential cellular mechanisms. The flexibility of a DNA fragment can be experimentally and computationally examined by its propensity for cyclization, quantified by the Jacobson-Stockmayer J factor. In...

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Detalles Bibliográficos
Autores principales: Alexandrov, Ludmil B., Bishop, Alan R., Rasmussen, Kim Ø., Alexandrov, Boian S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743258/
https://www.ncbi.nlm.nih.gov/pubmed/26846597
http://dx.doi.org/10.1186/s12859-016-0897-9