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Pitfalls of antiretroviral drug resistance genotyping of HIV-1 Group M and Group N from Cameroon by sequenced-based assays

BACKGROUND: HIV-1 genotyping for antiretroviral drug resistance mutations (DRMs) were developed based basically on subtype B HIV-1 Group M, which represents only 10% of HIV strains worldwide. In sub-Saharan Africa, non-B subtypes HIV-1 largely predominate and HIV-1 genetic diversity could affect the...

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Detalles Bibliográficos
Autores principales: Jenabian, Mohammad-Ali, Talla, Frédéric, Talla, Perrine, Mbopi-Kéou, François-Xavier, Charpentier, Charlotte, Kane, Coumba Toure, Bélec, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743293/
https://www.ncbi.nlm.nih.gov/pubmed/26903701
http://dx.doi.org/10.4103/0300-1652.171613