Haplo-insufficiency of both BubR1 and SGO1 accelerates cellular senescence

BACKGROUND: Spindle assembly checkpoint components BubR1 and Sgo1 play a key role in the maintenance of chromosomal instability during cell division. These proteins function to block the anaphase entry until all condensed chromosomes have been attached by the microtubules emanating from both spindle...

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Detalles Bibliográficos
Autores principales: Park, Sung-Hyun, Xie, Steve, Rao, Chinthalapally V., Dai, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743409/
https://www.ncbi.nlm.nih.gov/pubmed/26847209
http://dx.doi.org/10.1186/s13045-016-0238-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743409/
https://www.ncbi.nlm.nih.gov/pubmed/26847209
http://dx.doi.org/10.1186/s13045-016-0238-5

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